SMC NEWS & MARKET BRIEFINGS

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Stock Market Chat reporting built from verified public sources, with direct citations, SMC context, and uncertainty kept visible.

XRTX

XORTX Outlines Anticipated Health Canada Clinical Trial Application for XRx-026 for Gout

XORTX Therapeutics announced an anticipated Clinical Trial Application planned for filing with Health Canada for XRx-026 (XORLO™), describing a two-part study XRX-OXY-102 that will evaluate their proprietary oxypurinol formulation in gout. The company says conducting part one in Canada is intended to support its planned NDA filing with the U.S. Food and Drug Administration.

· SMC Research

MLYS

Mineralys Therapeutics Presents New Data for Lorundrostat at the American Heart Association Hypertension Scientific Sessions 2026

Mineralys reported new analyses from its Phase 3 Launch-HTN trial showing that 46% of lorundrostat-treated participants reached office systolic blood pressure <130 mmHg at 12 weeks and that 70% achieved ≥10 mmHg SBP reduction. Separate Phase 2 Explore-OSA results showed an 11.1 mmHg morning SBP reduction at Week 4 with lorundrostat 50 mg and no measurable change in apnea-hypopnea indices; the company reports no significant safety signals.

· SMC Research

LHX

NASA Awards L3Harris Contract to Build All Glass Telescope for LISA Mission

L3Harris Technologies says NASA selected the company to design, assemble, integrate and test a telescope for the European Space Agency-led Laser Interferometer Space Antenna (LISA) mission. The release describes a ceramic glass telescope and prior prototype work guiding flight-hardware development at NASA’s Goddard Space Flight Center.

· SMC Research

BIAF

bioAffinity Technologies, Inc. Announces Approximately $4 Million Registered Direct Financing of Common Stock and Concurrent Private Placement Priced At-The-Market Under Nasdaq Rules

bioAffinity Technologies announced a registered direct offering and a concurrent private placement expected to generate approximately $4 million in gross proceeds. The transaction terms include common stock (or pre-funded warrants) priced at $6.122 (or $6.115 per pre-funded warrant) and warrants for up to 980,072 shares exercisable after stockholder approval.

· SMC Research

NVDA

NVIDIA Commits $1 Billion to Advance US Science Over the Next Five Years

NVIDIA announced commitments valued at $1 billion to support U.S. scientific research and super intelligence over the next five years, targeting areas the company described as critical for U.S. leadership including quantum computing, healthcare and energy security. The company framed the funding as support for higher-education research institutions, quantum investments, and cloud providers serving U.S. government mission needs.

· SMC Research

BIAF

bioAffinity Technologies Announces Notification of Japanese Patent Allowance Covering Noninvasive CyPath® Lung and AI-Built Algorithm

bioAffinity Technologies announced that the Japan Patent Office has issued a Notice of Allowance for a patent covering its CyPath Lung method that combines automated flow cytometry and machine learning. The company described the patent as the first in Japan for CyPath Lung driven by an AI-built algorithm and highlighted prior patents and clinical performance metrics for the test.

· SMC Research

CYAB

Cyabra Secures Enterprise Agreement with Fortune 500 Media and Entertainment Company

Cyabra, Inc. (Nasdaq: CYAB) announced an enterprise agreement with a Fortune 500 global media and entertainment conglomerate to deploy its AI narrative intelligence platform to the company's marketing, communications, and security teams. The company says the engagement expands its commercial footprint and validates demand for disinformation security and narrative protection.

· SMC Research

BYRN

Byrna Technologies Reports Fiscal Third Quarter 2026 Results

Byrna Technologies reported fiscal Q3 2026 net revenue of $15.3 million and gross profit of $12.2 million (79% of net revenue), including a one-time $2.3 million tariff refund. The company reported a net loss of $(2.9) million for the quarter, noted adjusted gross margin of approximately 65% excluding the tariff item, and highlighted operational actions including an acquisition, outsourced ammunition production, and marketing initiatives.

· SMC Research

MYND

Mynd.ai Announces CEO and CFO Transition

Mynd.ai announced that Arthur Giterman will step down as CEO and CFO effective October 11, 2026, and resign from the Board the same day. The Board appointed Bin Shen as Chief Executive Officer and Interim Chief Financial Officer effective October 12, 2026; the company says it will search for a permanent CFO.

· SMC Research

VEEE

USFM and Twin Vee Amend Merger Agreement

USFM Corporation and Twin Vee PowerCats Co. amended their July 12, 2026 definitive merger agreement to change the transaction structure, add a requirement for USFM to seek an up to $5 million PIPE, and adjust the post-closing ownership split to 93% pre-closing USFM stockholders / 7% pre-closing Twin Vee stockholders. The parties expect closing in the fourth quarter of 2026 or the first quarter of 2027, subject to customary conditions.

· SMC Research

AAPL

Apple, The King’s Trust launch initiative to empower young creatives

Apple and The King’s Trust announced the Apple x King’s Trust Creative Labs, an immersive education program in London that will start with a cohort of up to 20 young people ages 18 to 30 and run workshops aligned with the recent opening of Apple Music Hall. The initiative builds on an existing partnership that includes STEAM programming, a 12-week Team program, and commitments to AI literacy resources.

· SMC Research

PROF

Profound Medical Reports Strong Preliminary Third Quarter 2026 Revenue

Profound Medical announced preliminary unaudited third quarter 2026 revenue expected in the range of $9.8 million to $10.0 million, a figure the company says is above Wall Street expectations, with gross margin expected to exceed 70%. The company will report audited results after market close on Thursday, November 5, 2026 and hold a conference call at 4:30 p.m. ET.

· SMC Research

NVS

Novartis Rhapsido® (remibrutinib) receives FDA approval as first treatment for symptomatic dermographism (SD), expanding its use beyond chronic spontaneous urticaria (CSU) In Phase III RemIN...

Novartis announced FDA approval of Rhapsido (remibrutinib) for adults with symptomatic dermographism (SD) inadequately controlled by H1 antihistamines, based on the SD cohort of the Phase III RemIND trial where Rhapsido produced higher rates of complete hive resolution versus placebo by Week 12. The company reports a safety profile in SD consistent with CSU and no routine laboratory monitoring required.

· SMC Research

ONDS

Ondas Secures Over $165 Million in New Orders Since Last Order Update

Ondas Inc. reported securing more than $165 million in aggregate orders between the second half of August and October 1, 2026, bringing orders secured since June 30 to over $270 million when combined with approximately $105 million previously disclosed. The company said order activity was broad-based and that key programs ULTRA and IonStrike advanced through customer validation milestones, expanding backlog and revenue visibility into 2027.

· SMC Research

RNXT

RenovoRx Advances TAMP™ into Borderline Resectable Pancreatic Cancer with First Patient Enrolled in Investigator-Initiated PRISM-TAMP Trial

RenovoRx reported that the first patient has enrolled in PRISM-TAMP, an investigator-initiated trial sponsored by the University of Vermont testing intra-arterial gemcitabine delivered via the RenovoCath TAMP platform as neoadjuvant therapy in borderline resectable pancreatic ductal adenocarcinoma. The study will assess tumor regression, intraoperative surgical margins, and safety as UVM plans to enroll approximately 10 patients.

· SMC Research